Frontal fibrosing alopecia. Authoritative facts about the skin from DermNet New Zealand. Frontal fibrosing alopecia is a disorder resulting in hair loss at the temples and front of the scalp. Learn about the causes and treatment of FFA. BackgroundFrontal fibrosing alopecia is considered a particular clinical form of lichen planopilaris that primarily involves the scalp hair over the frontal hai.

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Get free access to newly published articles. The etiology of FFA remains unknown.

Sincethere have been several reports of the use of the antidiabetic agent pioglitazone off-label for the treatment of frontal fibrosing alopecia. Back to top Article Information.

Hormone replacement does not appear to prevent the appearance of FFA.

You may find that joining a patient support group see below and meeting other people with alopecia will make it easier for you to adjust to your condition. Concomitant involvement of alipecia at different body sites has recently been reported. The relative rarity of FFA in men may reflect the earlier onset of this pattern of androgenic alopecia in men when immune frontzl is intact. Often the condition does become inactive over time.

A year-old postmenopausal woman presented with frontal hairline recession that had started 3 months before her visit to the clinic; peripilar inflammation had developed in the same region. It involves taking a small piece of skin from the scalp under local anaesthetic, which is then examined under a microscope. Approximately half of all cases of FFA also have eyebrow loss; less often there is hair loss in other parts of the body. The skin left behind may appear slightly paler and smoother than the rest of the skin on the forehead.


Some individuals with alopecia will prefer to wear a wig. The incidence of nonscalp vellus involvement is not known, with published data showing great variation.

Frontal fibrosing alopecia | DermNet NZ

Ultimately, the process tends to stabilize frontap is very slowly progressive, making assessment of therapeutic efficacy difficult, as hair regrowth is not achieved in areas of total loss. These treatments work by maintaining levels of testosterone a hormone naturally found in men and women in the hair follicles.

Fubrosing lichenoid reaction in FFA targets and destroys the follicular sheaths and stem cell region, but spares the interfollicular epidermis and also the lower follicle and hair bulb region. Isolated reports of men with this form of alopecia have also been documented.

This may occur with frontal fibrosing alopecia also contributing to hair loss.

Privacy Policy Terms of Use. Frontall skin biopsy examination in the laboratory may help to make or confirm the diagnosis. It tells you what frontal fibrosing alopecia FFA is, what causes it, what can be done about it and where alooecia can get more information.


Histopathologic testing of the scalp showed perifollicular fibrosis, eccentric atrophy of the follicular epithelium at the isthmus level, and foreign body reaction to the hair shaft inside the dermis.

Frontal fibrosing alopecia

Create a free personal account to download free article PDFs, sign up for alerts, and more. Once a hair has fallen out, it fibrossing not re-grow in this area. Back NMSC excision national re-audit This pattern fibrising seen much more frequently in men. Once hair loss that has already taken place it cannot be reversed. Sign in to access your subscriptions Sign in to your personal account. Drafting of the manuscript: Frontal recession and loss of eyebrows may be seen in alopecia areata.

In the frontal area, the loss may be more marked behind a preserved frontal hairline. By the time the medical consultation occurs, the process is often advanced. Demographic and Clinical Features.

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