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Modified IDSA/ATS Minor Criteria for Severe Community-Acquired Pneumonia Best Predicted Mortality

Ethical approval from the regulation committee Ethical Committee of Shenzhen was granted for the study protocol. Please review our privacy policy.

The simplification and modification were tested against the prospective 2 center validation cohort. The sensitivity, specificity, PPV, and Youden index of modified minor criteria for predicting mortality were the best pattern in the retrospective cohort.

Second, there were relatively small samples. Finally, the clinical outcomes data on ICU utilization were not collected. The receiver operating characteristic curves were created and the areas under the curves area under the receiver operating characteristic curves [AUCs] were calculated to illustrate and compare the accuracy of the indices.

Kelly et al 18 found that patients greater than 65 years of age had a higher incidence of altered mental status on presentation and that CURB scores and pneumonia severity index were higher in the older patients.

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Diagnosis, assessment of severity, antimicrobial therapy, and prevention. The validation cohort confirmed a similar pattern x 2P Therefore, all patients were regarded as receiving adequate antibiotics and were discharged home when they reached clinical stability and became afebrile. The validation cohort confirmed a similar pattern.

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National Center for Biotechnology InformationU. The simplification and modification were tested against a prospective 2-center validation cohort of adults with CAP. MJ was in charge of statistical analysis.

A total of patients were enrolled consecutively, and 15 cases were excluded from the retrospective cohort due to exclusion criteria. J Crit Care ; Laboratory variables were measured by the hospital clinical laboratories. This might be envisaged to interpret the reason why modified minor criteria was performed better than CURB score for the prediction of mortality in the validation cohort.

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Clin Infect Dis ; Eur Respir J ; Clinical and diagnostic data and radiological features were collected. How tubetculosis deal with the discrepancies?

This article has been cited by other articles in PMC. This article has been corrected. Guidelines for the management of adults with community-acquired pneumonia. Open in a separate window. Hence, further studies are warranted. The findings might have been more robust with a greater number of patients met the criteria.

The patients with CAP might be triaged more appropriately according to simplified minor criteria, and most accurately by using the modified version. Athe planned science and technology project of Shenzhen municipality in No. The sensitivities, specificities, positive predictive values PPVsnegative predictive values, and Youden indices were also calculated.

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Could it even be modified to orchestrate a further improvement? Which mechanism might be envisaged to interpret the effectiveness of the additional omission in the current study? Incorporation of the blood pressure criterion into a severity scoring system may lead to false negativity in the older people who have high prevalence of systolic hypertension owing to increasing age. Inadequate antimicrobial treatment of infections a risk factor for hospital mortality among critically ill patients.

Modified minor criteria was performed similarly for the tuuberculosis of mortality in the retrospective cohort, but better in the validation cohort, compared with CURB score. Clin Infect Dis ; 44 Suppl 2: First, this was a prospective 2 center, not a multicentre, validation cohort study. The frontal and lateral chest radiographic findings and computed tomographic scan images were classified independently by clasificaicon senior radiologists Liang and Zhao. The current findings might have implications for the management of the disease, especially at the emergency department, which may improve survival.

Weight of the CURB criteria for community-acquired pneumonia in a very low-mortality-rate setting. Future prospective clinical multicenter studies should also be performed to assess the generalizability. The hospital mortalities were 1.

This might be the causation.